The CHSR is focused on creating, testing and scaling next-generation solutions to improve the efficiency and effectiveness of health care delivery and the overall health of people within the Commonwealth. A primary objective of the center is to accelerate the discovery of new knowledge concerning clinical effectiveness and cost-effectiveness of health care delivery, particularly in rural and limited-resource settings. The undertaking, facilitating and coordinating of interprofessional collaborative research plays a crucial role in the Center's goal to optimize care. Through facilitating collaboration among colleges and centers at University of Kentucky, UK HealthCare®, Norton Health System, Appalachian Regional Healthcare, industrial partners, and health plans, the UK-CHSR can focus the expertise of University of Kentucky’s multiple colleges on advancing the science and innovation of care and achieving the goal of optimizing patient value through timely and relevant research. Research performed by members of the CHSR is aimed at identifying optimal methods to deliver high value health care rationally.

UK-CHSR focuses on five key areas of inquiry:
  •  Population Health
  •  Implementation Science
  •  Quality Measurement and Improvement
  •  Patient-Centered Outcomes and Comparative Effectiveness Research
  •  Health Informatics